It's the gesture.
You are speaking and the hand goes up...like Sex in the City 2 and Miranda ends up quitting her job.
This is the worst .
The hand just puts an end to everything - your thoughts, your momentum, your self -esteem.
What should you do?
Politely ask the gesture-er to not do that, let them know how insulting it is, and how to better go about getting a space in the conversation.